Endothelial Dysfunction and Subsequent Decline in Glomerular Filtration Rate in Hypertensive Patients
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چکیده
منابع مشابه
Hypertension Endothelial Dysfunction and Subsequent Decline in Glomerular Filtration Rate in Hypertensive Patients
Background—Chronic kidney disease is a risk factor for cardiovascular disease, increasing all-cause mortality. Some evidence suggests that endothelial dysfunction is present in the early stages of renal insufficiency, but no data exist about its possible role in the progression of renal disease. Thus, we prospectively evaluated the effect of endothelial function on estimated glomerular filtrati...
متن کاملEndothelial dysfunction and subsequent decline in glomerular filtration rate in hypertensive patients.
BACKGROUND Chronic kidney disease is a risk factor for cardiovascular disease, increasing all-cause mortality. Some evidence suggests that endothelial dysfunction is present in the early stages of renal insufficiency, but no data exist about its possible role in the progression of renal disease. Thus, we prospectively evaluated the effect of endothelial function on estimated glomerular filtrati...
متن کاملIncreased Circulating Endothelial Apoptotic Microparticle to Endothelial Progenitor Cell Ratio Is Associated with Subsequent Decline in Glomerular Filtration Rate in Hypertensive Patients
BACKGROUND Recent research indicates hypertensive patients with microalbuminuria have decreased endothelial progenitor cells (EPCs) and increased levels of endothelial apoptotic microparticles (EMP). However, whether these changes are related to a subsequent decline in glomerular filtration rate (GFR) remains unclear. METHODS AND RESULTS We enrolled totally 100 hypertensive out-patients with ...
متن کاملchanges in leukocyte subpopulations with decline in glomerular filtration rate in patients with type 2 diabetes
recent studies suggested the role of white blood cells (wbcs) in the pathogenesis and complications of type 2 diabetes. increased wbc counts predict mortality in patients with chronic kidney disease (ckd). in this study alterations in wbc subpopulations in diabetic patients with non-dialysis dependent ckd are investigated. this was a cross-sectional study on 376 participants, including 272 d...
متن کاملDecline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality.
IMPORTANCE The established chronic kidney disease (CKD) progression end point of end-stage renal disease (ESRD) or a doubling of serum creatinine concentration (corresponding to a change in estimated glomerular filtration rate [GFR] of −57% or greater) is a late event. OBJECTIVE To characterize the association of decline in estimated GFR with subsequent progression to ESRD with implications f...
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ژورنال
عنوان ژورنال: Circulation
سال: 2010
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.110.940932